Brain reserve hypothesis in dementia.

  title={Brain reserve hypothesis in dementia.},
  author={Laura Fratiglioni and Hui-xin Wang},
  journal={Journal of Alzheimer's disease : JAD},
  volume={12 1},
The concept of brain reserve refers to the ability to tolerate the age-related changes and the disease related pathology in the brain without developing clear clinical symptoms or signs. A considerable body of biological research has documented that a number of factors including education, work complexity, social network, and leisure activities may contribute to this reserve allowing cognitive function to be maintained in old ages. Epidemiological studies have also related these factors to the… CONTINUE READING

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