Brain regional vulnerability to anaesthesia-induced neuroapoptosis shifts with age at exposure and extends into adulthood for some regions.

@article{Deng2014BrainRV,
  title={Brain regional vulnerability to anaesthesia-induced neuroapoptosis shifts with age at exposure and extends into adulthood for some regions.},
  author={Meng Deng and Rylon D Hofacer and Connie Jiang and Bernadin Joseph and Elizabeth A Hughes and Bing Jia and Steve C Danzer and Andreas W. Loepke},
  journal={British journal of anaesthesia},
  year={2014},
  volume={113 3},
  pages={443-51}
}
BACKGROUND General anaesthesia facilitates surgical operations and painful interventions in millions of patients every year. Recent observations of anaesthetic-induced neuronal cell death in newborn animals have raised substantial concerns for young children undergoing anaesthesia. However, it remains unclear why some brain regions are more affected than others, why certain neurones are eliminated while neighbouring cells are seemingly unaffected, and what renders the developing brain… CONTINUE READING
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