Brain region specificity of 3-nitropropionic acid-induced vulnerability of neurons involves cytochrome c oxidase.

@article{Singh2010BrainRS,
  title={Brain region specificity of 3-nitropropionic acid-induced vulnerability of neurons involves cytochrome c oxidase.},
  author={Shilpee Singh and Magdalena Misiak and Cordian Beyer and Susanne Arnold},
  journal={Neurochemistry international},
  year={2010},
  volume={57 3},
  pages={297-305}
}
Mitochondria play a pivotal role in the regulation of energy metabolism and apoptotic pathways. Properties and functions of mitochondria might render subsets of selectively vulnerable neurons intrinsically susceptible to a different extent to cellular stress and degeneration. We have investigated the effect of 3-nitropropionic acid (NPA), a mitochondrial… CONTINUE READING