Brain region-specific gene expression activation required for reconsolidation and extinction of contextual fear memory.

@article{Mamiya2009BrainRG,
  title={Brain region-specific gene expression activation required for reconsolidation and extinction of contextual fear memory.},
  author={Nori Mamiya and Hotaka Fukushima and Akinobu Suzuki and Zensai Matsuyama and Seiichi Homma and Paul W. Frankland and Satoshi Kida},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={2009},
  volume={29 2},
  pages={
          402-13
        }
}
During fear conditioning, animals learn an association between a previously neutral or conditioned stimulus (CS) and an aversive or unconditioned stimulus (US). Subsequent reexposure to the CS alone triggers two competing processes. Brief reexposure to the CS initiates reconsolidation processes that serve to stabilize or maintain the original CS-US memory. In contrast, more prolonged reexposure to the CS leads to the formation of an inhibitory extinction (CS-no US) memory. Previous studies have… CONTINUE READING

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References

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Memory reconsolidation and extinction have distinct temporal and biochemical signatures.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2004
VIEW 24 EXCERPTS
HIGHLY INFLUENTIAL

Stability of recent and remote contextual fear memory.

  • Learning & memory
  • 2006
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Consolidation of fear extinction requires protein synthesis in the medial prefrontal cortex.

  • The Journal of neuroscience : the official journal of the Society for Neuroscience
  • 2004
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL