Brain region and dose effects of an olanzapine/fluoxetine combination on extracellular monoamine concentrations in the rat.

@article{Koch2004BrainRA,
  title={Brain region and dose effects of an olanzapine/fluoxetine combination on extracellular monoamine concentrations in the rat.},
  author={Susanne Koch and Kenneth Perry and Frank P. Bymaster},
  journal={Neuropharmacology},
  year={2004},
  volume={46 2},
  pages={232-42}
}
Clinical studies of patients with treatment-resistant depression have shown that combined treatment with fluoxetine and olanzapine rapidly and significantly improved depressive symptoms. The present study used in vivo microdialysis to investigate the brain regional and dose effects of these drugs on extracellular monoamine concentrations in the rat… CONTINUE READING