Brain proton magnetic resonance spectroscopy and brain atrophy in myotonic dystrophy.

@article{Akiguchi1999BrainPM,
  title={Brain proton magnetic resonance spectroscopy and brain atrophy in myotonic dystrophy.},
  author={Ichiro Akiguchi and Satoshi Nakano and Akihiko Shiino and Ryo Kimura and Toshiro Inubushi and Jyoji Handa and Mitsuru Nakamura and Masaki Tanaka and Nobuo Oka and Jun Kimura},
  journal={Archives of neurology},
  year={1999},
  volume={56 3},
  pages={325-30}
}
OBJECTIVES To evaluate by magnetic resonance spectroscopy the age-related cerebral alterations present in myotonic dystrophy (MD) and to compare these results with those obtained by magnetic resonance imaging. DESIGN Twenty-one patients (aged 16-63 years) with MD were compared with 16 age-matched healthy control subjects. RESULTS In magnetic resonance spectroscopy, the mean (+/- SD) ratio of N-acetylaspartate to creatine and phosphocreatine in the patients with MD (1.09 +/- 0.32) was… CONTINUE READING
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