Brain processing of capsaicin-induced secondary hyperalgesia: a functional MRI study.

@article{Baron1999BrainPO,
  title={Brain processing of capsaicin-induced secondary hyperalgesia: a functional MRI study.},
  author={Ralf Baron and Y Baron and Elizabeth A. Disbrow and Timothy P. L. Roberts},
  journal={Neurology},
  year={1999},
  volume={53 3},
  pages={548-57}
}
OBJECTIVE To investigate, using functional MRI (fMRI), the neural network that is activated by the pain component of capsaicin-induced secondary mechanical hyperalgesia. BACKGROUND Mechanical hyperalgesia (i.e., pain to innocuous tactile stimuli) is a distressing symptom of neuropathic pain syndromes. Animal experiments suggest that alterations in central pain processing occur that render tactile stimuli capable of activating central pain-signaling neurons. A similar central sensitization can… CONTINUE READING

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