Brain processing during mechanical hyperalgesia in complex regional pain syndrome: a functional MRI study

  title={Brain processing during mechanical hyperalgesia in complex regional pain syndrome: a functional MRI study},
  author={C. Maih{\"o}fner and C. Forster and F. Birklein and B. Neundörfer and H. Handwerker},
  • C. Maihöfner, C. Forster, +2 authors H. Handwerker
  • Published 2005
  • Psychology, Medicine
  • Pain
  • &NA; Complex Regional Pain Syndromes (CRPS) are characterized by a triad of sensory, motor and autonomic dysfunctions of still unknown origin. Pain and mechanical hyperalgesia are hallmarks of CRPS. There are several lines of evidence that central nervous system (CNS) changes are crucial for the development and maintenance of mechanical hyperalgesia. However, little is known about the cortical structures associated with the processing of hyperalgesia in pain patients. This study describes the… CONTINUE READING
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    Paper Mentions

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    Reflex Sympathetic Dystrophy (RSD), Complex Regional Pain Syndrome (CRPS), Causalgia, and Fibromyalgia represent progressive systemic pain conditions which often worsen over time… Expand
    ConditionsCRPS - Complex Regional Pain Syndrome Type I, Fibromyalgia, RSD (Reflex Sympathetic Dystrophy)
    Interventional Clinical Trial
    Medical functional imagery seems to demonstrate that patients suffering from complex regional pain syndrome (CRPS) have cortical modifications that alter their motor (or mental) imagery… Expand
    ConditionsComplex Regional Pain Syndromes, Healthy, Musculoskeletal Pain Disorder
    InterventionDiagnostic Test
    The motor system shows adaptive changes in complex regional pain syndrome.
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