Brain plasticity in the motor network is correlated with disease progression in amyotrophic lateral sclerosis.

@article{Poujois2013BrainPI,
  title={Brain plasticity in the motor network is correlated with disease progression in amyotrophic lateral sclerosis.},
  author={Aur{\'e}lia Poujois and Fabien C. Schneider and Isabelle Faillenot and Jean-Philippe Camdessanch{\'e} and Nadia Vandenberghe and C. Thomas-Ant{\'e}rion and J F Antoine},
  journal={Human brain mapping},
  year={2013},
  volume={34 10},
  pages={2391-401}
}
OBJECTIVE To test the influence of functional cerebral reorganization in amyotrophic lateral sclerosis (ALS) on disease progression. METHODS Nineteen predominantly right-handed ALS patients and 21 controls underwent clinical evaluation, functional Magnetic Resonance Imaging (fMRI), and diffusion tensor imaging. Patients were clinically re-evaluated 1 year later and followed until death. For fMRI, subjects executed and imagined a simple hand-motor task. Between-group comparisons were performed… CONTINUE READING
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