Brain perfusion correlates of cognitive and nigrostriatal functions in de novo Parkinson’s disease

Abstract

Subtle cognitive impairment is recognized in the first stages of Parkinson’s disease (PD), including executive, memory and visuospatial dysfunction, but its pathophysiological basis is still debated. Twenty-six consecutive, drug-naïve, de novo PD patients underwent an extended neuropsychological battery, dopamine transporter (DAT) and brain perfusion single… (More)
DOI: 10.1007/s00259-011-1874-1

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