Brain perfusion abnormalities in Gilles de la Tourette's syndrome.

  title={Brain perfusion abnormalities in Gilles de la Tourette's syndrome.},
  author={J. J. Moriarty and Durval C. Costa and Bernd Schmitz and Michael Robert Trimble and Peter Joseph Ell and Mary May Robertson},
  journal={The British journal of psychiatry : the journal of mental science},
  volume={167 2},
BACKGROUND Functional brain imaging with technetium-99m d,l-hexamethyl propyleneamine oxime (HMPAO) Single Photon Emission Tomography (SPET) allows us to explore the cerebral pathophysiology of Gilles de la Tourette's Syndrome (GTS). METHOD Fifty patients and 20 controls were examined. Patients were rated for tic severity and mood. Scans were analysed quantitatively using internal ratios to the occipital cortex. RESULTS Patients different from controls on measures of relative blood flow to… CONTINUE READING


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