Brain oxidative stress in a triple-transgenic mouse model of Alzheimer disease.


Alzheimer disease (AD) is a neurodegenerative disease which is characterized by the presence of extracellular senile plaques mainly composed of amyloid-beta peptide (Abeta), intracellular neurofibrillary tangles, and selective synaptic and neuronal loss. AD brains revealed elevated levels of oxidative stress markers which have been implicated in Abeta… (More)
DOI: 10.1016/j.freeradbiomed.2008.03.012


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