Brain oxidative energy and related metabolism, neuronal stress, and Alzheimer's disease: a speculative synthesis.

@article{Hoyer1993BrainOE,
  title={Brain oxidative energy and related metabolism, neuronal stress, and Alzheimer's disease: a speculative synthesis.},
  author={Siegfried Hoyer},
  journal={Journal of geriatric psychiatry and neurology},
  year={1993},
  volume={6 1},
  pages={3-13}
}
  • Siegfried Hoyer
  • Published 1993 in Journal of geriatric psychiatry and neurology
A reduction in the cerebral metabolic rate of glucose is one of the most predominant abnormalities generally found in the Alzheimer brain, whereas the cerebral metabolic rate of oxygen is diminished only slightly or not at all at the beginning of this dementive disorder. From the cerebral metabolic rates of oxidized glucose and oxygen, the cerebral adenosine triphosphate (ATP) formation rate was calculated in incipient early-onset, incipient late-onset, and stable advanced dementia of the… CONTINUE READING

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