Brain organization for language from the perspective of electrical stimulation mapping

  title={Brain organization for language from the perspective of electrical stimulation mapping},
  author={George A. Ojemann},
  journal={Behavioral and Brain Sciences},
  pages={189 - 206}
  • G. Ojemann
  • Published 1 June 1983
  • Psychology
  • Behavioral and Brain Sciences
Abstract A model for the organization of language in the adult humans brain is derived from electrical stimulation mapping of several language-related functions: naming, reading, short-term verbal memory, mimicry of orofacial movements, and phoneme identification during neurosurgical operations under local anesthesia. A common peri-Sylvian cortex for motor and language functions is identified in the language dominant hemisphere, including sites common to sequencing of movements and… 
The neurobiology of language and verbal memory: observations from awake neurosurgery.
  • G. Ojemann
  • Psychology, Biology
    International journal of psychophysiology : official journal of the International Organization of Psychophysiology
  • 2003
Cortical language localization in left, dominant hemisphere. An electrical stimulation mapping investigation in 117 patients.
There is a need for revision of the classical model of language localization, for it means that language cannot be reliably localized on anatomic criteria alone and a maximal resection with minimal risk of postoperative aphasia requires individual localization of language with a technique like stimulation mapping.
Cortical Organization of Language and Verbal Memory Based on Intraoperative Investigations
Questions are raised about major features of the traditional model of the cortical organization of language, including evidence that permanent motor language deficits usually require lesions that extend well beyond Broca’s area, into inferior parietal and superior temporal lobe, and that language deficits after frontal lesion include not only expressive problems but also a receptive deficit, particularly for syntax.
Language Representation in the Human Brain: Evidence from Cortical Mapping
Three right-handed adult male neurosurgical patients undergoing left craniotomy for intractable seizures were evaluated using various grammatical and semantic tasks during cortical mapping to suggest that the representation of language in the human brain may be columnar or multilayered.
Language processing from the perspective of electrical stimulation mapping
The aim was to highlight ES as a tool to further the understanding of cognitive models of language and discussed parallels between the ES and the stroke literatures and showed how ES data can help to generate hypotheses regarding how language is processed.
Stimulating language: insights from TMS.
Fifteen years ago, Pascual-Leone and colleagues used transcranial magnetic stimulation (TMS) to investigate speech production in pre-surgical epilepsy patients and in doing so, introduced a novel
Human Temporal Cortical Single Neuron Activity during Language: A Review
Human single neuron recordings provide a unique perspective on the biologic substrate for language, for these findings are in contrast to many of the findings from other techniques for investigating this.


Language localization and variability
Human language cortex: localization of memory, syntax, and sequential motor-phoneme identification systems.
Subdivisions of the human peri-Sylvian language cortex were derived from stimulation mapping during craniotomies under local anesthesia and identified a common system for language production and understanding.
Individual variability in cortical localization of language.
  • G. Ojemann
  • Medicine, Psychology
    Journal of neurosurgery
  • 1979
The classical model of language localization is an inaccurate basis for establishing the risk of aphasia in surgical therapy of dominant hemisphere peri-Sylvian lesions in this and related patient populations because of high degree of variability in the exact location of naming.
Mechanism and localization of speech in the parietotemporal cortex.
Observations of the disintegration of speech function during stimulation suggest that such stimulation interferes with a search mechanism by which the nonverbal concept of a visual stimulus is linked to a specific word in memory that is then withdrawn for use.
Variability in right hemisphere language function after callosal section: evidence for a continuum of generative capacity
The right hemisphere language systems in both patients were shown to be capable of semantic information processing, but they differed in their abilities to process phonetic information, follow verbal commands, and produce linguistic responses.
Language-related potentials specific to human language cortex.
Event-related potentials following silently named object pictures were recorded directly from the exposed left hemisphere of the human cortex at sites whose relation to naming was subsequently
Sex differences in human brain asymmetry: a critical survey
  • J. Mcglone
  • Psychology, Biology
    Behavioral and Brain Sciences
  • 1980
Abstract Dual functional brain asymmetry refers to the notion that in most individuals the left cerebral hemisphere is specialized for language functions, whereas the right cerebral hemisphere is