Brain nitric oxide synthases in the interleukin-1β-induced activation of hypothalamic-pituitary-adrenal axis.

@article{GdekMichalska2012BrainNO,
  title={Brain nitric oxide synthases in the interleukin-1β-induced activation of hypothalamic-pituitary-adrenal axis.},
  author={Anna Gądek-Michalska and Joanna Tadeusz and Paulina Rachwalska and Jadwiga Spyrka and Jan Bugajski},
  journal={Pharmacological reports : PR},
  year={2012},
  volume={64 6},
  pages={1455-65}
}
BACKGROUND Interleukin-1β (IL-1β), the major cytokine involved in activation of hypothalamic-pituitary-adrenal (HPA) axis modulates both central and peripheral components regulating HPA activity. The role of nitric oxide (NO) generated by neuronal nitric oxide synthase (nNOS) and inducible nitric oxide synthase (iNOS) in brain structures involved in HPA axis regulation has not been elucidated. The aim of the study was to assess the receptor selectivity of IL-1β stimulatory action on HPA axis… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 10 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 40 references

Nussdorfer GG: Interleukin-1b enhances Pharmacological Reports

  • PG Andreis, G Neri, AS Belloni, G Mazzocchi, A Kasprzak
  • Endocrinology,
  • 2012
2 Excerpts

Effect of prior stress on imterleukin-1b and HPA axis responses to acute stress

  • J Tadeusz, P Rachwalska, J Spyrka, J Bugajski
  • Pharmacol Rep,
  • 2011
2 Excerpts

Similar Papers

Loading similar papers…