Brain natriuretic peptide and left ventricular dysfunction in Chagas' disease.

@article{Ribeiro2002BrainNP,
  title={Brain natriuretic peptide and left ventricular dysfunction in Chagas' disease.},
  author={Ant{\^o}nio Luiz Pinho Ribeiro and Adelina Martha dos Reis and M{\'a}rcio Vin{\'i}cius Lins de Barros and Marcos Roberto de Sousa and Ana Luiza Lunardi Rocha and Amanda Arantes Perez and Jacqueline Braga Pereira and Fernando S. Machado and Manoel {\'O}tavio da Costa Rocha},
  journal={Lancet},
  year={2002},
  volume={360 9331},
  pages={461-2}
}
Left ventricular dysfunction in Chagas' disease is common but can be difficult to detect. We investigated whether measurement of plasma brain natriuretic peptide (BNP) could identify patients with left ventricular dysfunction who need further investigation or treatment. Among patients with an abnormal electrocardiogram or chest radiograph, a BNP concentration of 60.7 pmol/L or higher has a sensitivity and positive predictive value of 80%, and specificity and negative predictive value of 97… CONTINUE READING

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