Brain microvessels: factors altering their patency after the occlusion of a middle cerebral artery (Wistar rat).

@article{Garcia1994BrainMF,
  title={Brain microvessels: factors altering their patency after the occlusion of a middle cerebral artery (Wistar rat).},
  author={Julio H. Garcia and Katharine Liu and Yoshihiro Yoshida and Shiuhwei Chen and J. Lian},
  journal={The American journal of pathology},
  year={1994},
  volume={145 3},
  pages={728-40}
}
The progression from ischemic injury to pannecrosis that occurs in the rat brain several hours after occluding a large artery may be partly attributable to a worsening of the circulation through the microvessels. The objective of this study was to quantitate selected structural changes involving astrocytes and endothelial cells within an area of focal brain ischemia created by the occlusion of a middle cerebral artery. The magnitude of these structural changes was correlated with alterations in… CONTINUE READING