Brain metastasis in melanoma: clinical activity of CTLA-4 antibody therapy.

Abstract

Melanoma metastasizes frequently to the brain, and brain metastases generally drive the prognosis of melanoma patients. Surgical and radiation therapy improve the outcome of selected melanoma patients with brain metastasis, while systemic treatment using cytotoxic agents still plays a limited role. Temozolomide and fotemustine are preferentially used in… (More)
DOI: 10.1053/j.seminoncol.2010.09.014

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Cite this paper

@article{Margolin2010BrainMI, title={Brain metastasis in melanoma: clinical activity of CTLA-4 antibody therapy.}, author={Kim A Margolin and Anna Maria Di Giacomo and Michele Di Maio}, journal={Seminars in oncology}, year={2010}, volume={37 5}, pages={468-72} }