Brain metabolite changes in cortical grey and normal-appearing white matter in clinically early relapsing-remitting multiple sclerosis.

@article{Chard2002BrainMC,
  title={Brain metabolite changes in cortical grey and normal-appearing white matter in clinically early relapsing-remitting multiple sclerosis.},
  author={D T Chard and Colette M B Griffin and Mary Ann McLean and Peter Kapeller and Raju Kapoor and Alan J. Thompson and David H. Miller},
  journal={Brain : a journal of neurology},
  year={2002},
  volume={125 Pt 10},
  pages={2342-52}
}
While much work has concentrated on focal white matter (WM) lesions in multiple sclerosis, there is growing evidence to suggest that normal-appearing WM (NAWM) and grey matter (GM) are also involved in the disease process. This study investigated multiple sclerosis disease effects on NAWM and cortical GM (CGM) metabolite concentrations, and the… CONTINUE READING