Brain metabolism in Alzheimer disease and vascular dementia assessed by in vivo proton magnetic resonance spectroscopy.

@article{Herminghaus2003BrainMI,
  title={Brain metabolism in Alzheimer disease and vascular dementia assessed by in vivo proton magnetic resonance spectroscopy.},
  author={Sebastian Herminghaus and Lutz Fr{\"o}lich and Corrina Gorriz and Ullrich Pilatus and Thomas Dierks and Hans-J{\"o}rg Wittsack and Heinrich Lanfermann and Konrad Maurer and Friedhelm E. Zanella},
  journal={Psychiatry research},
  year={2003},
  volume={123 3},
  pages={183-90}
}
Proton magnetic resonance spectroscopy (MRS) allows the assessment of various cerebral metabolites non-invasively in vivo. Among 1H MRS-detectable metabolites, N-acetyl-aspartate and N-acetyl-aspartyl-glutamate (tNAA), trimethylamines (TMA), creatine and creatine phosphate (tCr), inositol (Ins) and glutamate (Gla) are of particular interest, since these moieties can be assigned to specific neuronal and glial metabolic pathways, membrane constituents, and energy metabolism. In this study on 94… CONTINUE READING
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