Brain magnetic resonance imaging helps to differentiate atypical multiple sclerosis with cavitary lesions and vanishing white matter disease

  title={Brain magnetic resonance imaging helps to differentiate atypical multiple sclerosis with cavitary lesions and vanishing white matter disease},
  author={Xavier Ayrignac and Nicolas Menjot de Champfleur and S Menjot de Champfleur and Clarisse Carra-Dalli{\`e}re and J{\'e}r{\'e}my Deverdun and Astrid Corlob{\'e} and Pierre Labauge},
  journal={European Journal of Neurology},
BACKGROUND AND PURPOSE Multiple sclerosis (MS) patients can present with atypical cavitary lesions mimicking vanishing white matter disease (VWMD. [] Key MethodMETHODS A cross-sectional study was performed including 14 patients with MS with cavitary lesions and 14 patients with VWMD. Two neuroradiologists retrospectively reviewed the MRI including at least T1-, T2- and fluid-attenuated inversion recovery weighted images.
Familial deep cavitating state with a glutathione metabolism defect
Investigations realized in patients referred for psychiatric disorder with magnetic resonance imaging showing atypical basal ganglia lesions revealed a new hereditary disease linked to glutathione metabolism.
Genetic diseases mimicking multiple sclerosis
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In this review, the main pattern of presentation of atypical inflammatory demyelinating diseases is discussed, with particular attention on the differential diagnosis and how to adequately define the correct etiology.
Automated segmentation reveals silent radiographic progression in adult-onset vanishing white-matter disease
The results of an automated method of segmentation to detect alterations in T2-weighted fluid-attenuated-inversion-recovery (FLAIR) sequences in a one-year follow-up study of a clinically stable patient with genetically diagnosed VWM demonstrate that automated EVD-based segmentation allows a precise and rapid quantification of extensive FLAIR alterations like in VWM.
MRI Findings in Tumefactive Demyelinating Lesions: A Systematic Review and Meta-Analysis
Conventional MR imaging findings may help differentiate tumefactive demyelinating lesions from primary brain tumor, though further study is needed to determine the added value of advanced MR imaging.
Vanishing white matter disease
Advances and insights into neurological practice 2016−17
  • A. Schapira
  • Medicine, Psychology
    European journal of neurology
  • 2017
Stroke represents the largest proportion of papers published, including those on pathophysiology, acute stroke management, and the outcome of patients who have suffered stroke.


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