Brain lipid sensing and nervous control of energy balance.

  title={Brain lipid sensing and nervous control of energy balance.},
  author={St{\'e}phanie Migrenne and Christelle Le Foll and By E. Levin and Christophe Magnan},
  journal={Diabetes & metabolism},
  volume={37 2},
Nutrient sensitive neurons (glucose and fatty acids (FA)) are present in many sites throughout the brain, including the hypothalamus and brainstem, and play a key role in the neural control of energy and glucose homeostasis. Through neuronal output, FA may modulate feeding behaviour as well as both insulin secretion and action. For example, central administration of oleate inhibits food intake and glucose production in rats. This suggests that daily variations in plasma FA concentrations might… CONTINUE READING
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