Brain injury in experimental neonatal meningitis due to group B streptococci.

@article{Kim1995BrainII,
  title={Brain injury in experimental neonatal meningitis due to group B streptococci.},
  author={Young Shin Kim and Roy A. Sheldon and Berkley R Elliott and Q Y Liu and Donna M. Ferriero and Martin George T{\"a}uber},
  journal={Journal of neuropathology and experimental neurology},
  year={1995},
  volume={54 4},
  pages={
          531-9
        }
}
We have characterized the pattern of brain injury in a rat model of meningitis caused by group B streptococci (GBS). Infant rats (12-14 days old; n = 69) were infected intracisternally with 10 microliters of GBS (log10(2.3) to 4.5 colony-forming units). Twenty hours later, illness was assessed clinically and cerebrospinal fluid was cultured. Animals were either immediately euthanized for brain histopathology or treated with antibiotics and examined later. Early GBS meningitis was characterized… CONTINUE READING
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