Brain injury-dependent expression of activity-dependent neuroprotective protein

@article{Zaltzman2004BrainIE,
  title={Brain injury-dependent expression of activity-dependent neuroprotective protein},
  author={Roy Zaltzman and A. E. Alexandrovich and Sara M. Beni and Victoria Trembovler and Esther Shohami and Illana Gozes},
  journal={Journal of Molecular Neuroscience},
  year={2004},
  volume={24},
  pages={181-187}
}
Activity-dependent neuroprotective protein (ADNP), a crucial brain development factor, contains a unique sequence, termed NAPVSIPQ, which protects mice against closed head injury (CHI). The aim of this study was to determine whether CHI affects ADNP mRNA expression in the injured brain hemisphere. Male C57JBL/6J mice were subjected to CHI. Brains were removed 5 h, 24 h, 7 d, and 29 d post-CHI. A comparison was made between ADNP mRNA in the injured versus the noninjured hemisphere using real… CONTINUE READING