Brain imaging in catatonia: systematic review and directions for future research

@article{Haroche2020BrainII,
  title={Brain imaging in catatonia: systematic review and directions for future research},
  author={Alexandre Haroche and Jonathan P Rogers and Marion Plaze and Raphael Gaillard and Steve C. R. Williams and Pierre Thomas and Ali Amad},
  journal={Psychological Medicine},
  year={2020},
  volume={50},
  pages={1585 - 1597}
}
Abstract Background Catatonia is a frequent, complex and severe identifiable syndrome of motor dysregulation. However, its pathophysiology is poorly understood. Methods We aimed to provide a systematic review of all brain imaging studies (both structural and functional) in catatonia. Results We identified 137 case reports and 18 group studies representing 186 individual patients with catatonia. Catatonia is often associated with brain imaging abnormalities (in more than 75% of cases). The… Expand
Brainstem alterations contribute to catatonia in schizophrenia spectrum disorders
TLDR
MRI results support a neuromechanistically important role of brainstem structures in catatonia in SSD, particularly in motor symptom expression. Expand
The fMRI signature of acute catatonic state and its response to benzodiazepines
TLDR
Functional MRI markers that characterize the acute retarded catatonic state and predict treatment response are identified and discuss how these novel findings have important translational implications for understanding the pathophysiology of catatonia and for predicting treatment response to benzodiazepines. Expand
Clinical features and predictors of non-response in severe catatonic patients treated with electroconvulsive therapy
TLDR
The association between ECT resistant catatonia and neurological comorbidity, use of dopamine-agonist and anticholinergic medications is consistent with the hypothesis that ECT is more effective in ‘top-down’ than in � ‘bottom-up’ variant of cat atonia. Expand
Pediatric Malignant Catatonia Associated With Vaporized Cannabis Use: A Case Series.
TLDR
Given the increasing popularity of vaporized cannabis use among adolescents, malignant catatonia should be on the differential in a pediatric patient presenting with psychomotor disturbances and autonomic instability. Expand
Die sensomotorische Domäne im Research-Domain-Criteria-System: Fortschritte und Perspektiven
In den vergangenen drei Jahrzehnten ist das Forschungsinteresse an sensomotorischen Auffälligkeiten bei psychischen Erkrankungen stetig gewachsen. Dieser Trend hat zu einer zunehmenden AnzahlExpand
Resting state functional connectivity and structural abnormalities of the brain in acute retarded catatonia: an exploratory MRI study
In this first cross-sectional MRI study in acute catatonia, we compared the resting state whole-brain, within-network and seed (left precentral gyrus)-to-voxel connectivity, as well as corticalExpand
Asylum-seeking children in shutdown: Neurobiological models
Asylum-seeking children presenting in the shutdown state have been the subject of much discussion and controversy—on both government and medical system levels—in Australia and in Sweden. In thisExpand

References

SHOWING 1-10 OF 52 REFERENCES
Brain Imaging in Catatonia: Current Findings and a Pathophysiologic Model
TLDR
Brain imaging studies have shown major and specific alterations in a right hemispheric neural network that includes the medial and lateral orbitofrontal and posterior parietal cortex that may be abnormally modulated by altered functional interactions between γ-aminobutyric acid-ergic and glutamatergic transmission. Expand
Structure and neural mechanisms of catatonia.
TLDR
Evidence from brain imaging studies of patients with psychotic disorders indicates increased neural activity in premotor areas in patients with hypokinetic catatonia, but whether this localised hyperactivity is due to corticocortical inhibition or excess activity of inhibitory corticobasal ganglia loops is unclear. Expand
Multimodal Magnetic Resonance Imaging Data Fusion Reveals Distinct Patterns of Abnormal Brain Structure and Function in Catatonia.
TLDR
A multivariate data fusion technique for multimodal magnetic resonance imaging data is used to investigate patterns of aberrant intrinsic neural activity (INA) and gray matter volume (GMV) in SSD patients with and without catatonia, suggesting co-altered structure/function-interactions in neural systems subserving coordinated visuospatial functions and motor behavior. Expand
Resting-State Hyperperfusion of the Supplementary Motor Area in Catatonia
TLDR
Resting-state cerebral blood flow (rCBF) and gray matter (GM) density between schizophrenia patients with current catatonia and without cat atonia and healthy controls is compared to argue for distinct pathobiology. Expand
Catatonia and neuroleptic malignant syndrome: psychopathology and pathophysiology
TLDR
One may characterize catatonia as a cortical “psychomotor syndrome” while NMS may rather be regarded as subcortical “motor Syndrome”. Expand
Cortical Contributions to Distinct Symptom Dimensions of Catatonia.
TLDR
T1-weighted structural magnetic resonance imaging data at 3 T were obtained from 56 right-handed patients with SSD and support the notion that cortical features of distinct evolutionary and genetic origin differently contribute to catatonia in SSD. Expand
Right lower prefronto-parietal cortical dysfunction in akinetic catatonia: a combined study of neuropsychology and regional cerebral blood flow
TLDR
Findings are preliminary but suggest right lower prefronto-parietal cortical dysfunction in catatonia, which may be closely related to psychomotor disturbances. Expand
Orbitofrontal cortical dysfunction in akinetic catatonia: a functional magnetic resonance imaging study during negative emotional stimulation.
TLDR
Catatonic symptoms may be closely related to dysfunction in the orbitofrontal cortex and consequent alteration in the prefrontal cortical network during emotional processing and interpreted as a trait marker predisposing for development of catatonic syndrome in schizophrenic or affective psychosis. Expand
What catatonia can tell us about “top-down modulation”: A neuropsychiatric hypothesis
  • G. Northoff
  • Medicine, Psychology
  • Behavioral and Brain Sciences
  • 2002
TLDR
It is hypothesized that similarities and differences between Parkinson's disease and catatonia may be accounted for by distinct kinds of modulation between Cortico-cortical and cortico-subcortic relations. Expand
Cortical sulcal enlargement in catatonic schizophrenia: a planimetric CT study
TLDR
Catatonic schizophrenia, the most severe sub-type with regard to clinical symptomatology and brain pathology, showed fronto-parietal cortical alterations and hebephrenic schizophrenia was characterised by lower frontal (i.e. orbitofrontal) enlargement. Expand
...
1
2
3
4
5
...