Brain imaging in Alzheimer disease.

  title={Brain imaging in Alzheimer disease.},
  author={Keith A. Johnson and Nick C. Fox and Reisa A. Sperling and William E. Klunk},
  journal={Cold Spring Harbor perspectives in medicine},
  volume={2 4},
Imaging has played a variety of roles in the study of Alzheimer disease (AD) over the past four decades. Initially, computed tomography (CT) and then magnetic resonance imaging (MRI) were used diagnostically to rule out other causes of dementia. More recently, a variety of imaging modalities including structural and functional MRI and positron emission tomography (PET) studies of cerebral metabolism with fluoro-deoxy-d-glucose (FDG) and amyloid tracers such as Pittsburgh Compound-B (PiB) have… CONTINUE READING
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