Brain glycogen in health and disease.

@article{Duran2015BrainGI,
  title={Brain glycogen in health and disease.},
  author={Jordi Busquets Duran and Joan J. Guinovart},
  journal={Molecular aspects of medicine},
  year={2015},
  volume={46},
  pages={
          70-7
        }
}
Glycogen is present in the brain at much lower concentrations than in muscle or liver. However, by characterizing an animal depleted of brain glycogen, we have shown that the polysaccharide plays a key role in learning capacity and in activity-dependent changes in hippocampal synapse strength. Since glycogen is essentially found in astrocytes, the diverse roles proposed for this polysaccharide in the brain have been attributed exclusively to these cells. However, we have demonstrated that… CONTINUE READING
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