Brain glycogen content and metabolism in subjects with type 1 diabetes and hypoglycemia unawareness.

@article{z2012BrainGC,
  title={Brain glycogen content and metabolism in subjects with type 1 diabetes and hypoglycemia unawareness.},
  author={G{\"u}lin {\"O}z and Nolawit Tesfaye and Anjali F. Kumar and Dinesh K Deelchand and Lynn E. Eberly and Elizabeth R Seaquist},
  journal={Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism},
  year={2012},
  volume={32 2},
  pages={
          256-63
        }
}
Supercompensated brain glycogen may contribute to the development of hypoglycemia unawareness in patients with type 1 diabetes by providing energy for the brain during periods of hypoglycemia. Our goal was to determine if brain glycogen content is elevated in patients with type 1 diabetes and hypoglycemia unawareness. We used in vivo (13)C nuclear magnetic resonance spectroscopy in conjunction with [1-(13)C]glucose administration in five patients with type 1 diabetes and hypoglycemia… CONTINUE READING

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