Brain glycogen and its role in supporting glutamate and GABA homeostasis in a type 2 diabetes rat model.

@article{Sickmann2012BrainGA,
  title={Brain glycogen and its role in supporting glutamate and GABA homeostasis in a type 2 diabetes rat model.},
  author={Helle Mark Sickmann and Helle S\onderby Waagepetersen and Arne Schousboe and Andrew James Benie and Stephan Daniel Bouman},
  journal={Neurochemistry international},
  year={2012},
  volume={60 3},
  pages={267-75}
}
The number of people suffering from diabetes is hastily increasing and the condition is associated with altered brain glucose homeostasis. Brain glycogen is located in astrocytes and being a carbohydrate reservoir it contributes to glucose homeostasis. Furthermore, glycogen has been indicated to be important for proper neurotransmission under normal conditions. Previous findings from our laboratory suggested that glucose metabolism was reduced in type 2 diabetes, and thus we wanted to… CONTINUE READING
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