Brain glutamate dehydrogenase changes in streptozotocin diabetic rats as a function of age.

@article{Biju1998BrainGD,
  title={Brain glutamate dehydrogenase changes in streptozotocin diabetic rats as a function of age.},
  author={Mangatt P. Biju and Cheramadathikudyil Skaria Paulose},
  journal={Biochemistry and molecular biology international},
  year={1998},
  volume={44 1},
  pages={1-7}
}
Kinetic parameters of brain glutamate dehydrogenase (GDH) were compared in the brain stem, cerebellum and cerebral cortex of three weeks and one year old streptozotocin (STZ) induced four day diabetic rats with respective controls. A single intrafemoral dose of STZ (60 mg/Kg body weight) was administered to induce diabetes in both age groups. After four days the blood glucose levels showed a significant increase in the diabetic animals of both age groups compared with the respective controls… CONTINUE READING

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