Brain glucose metabolism in hypothyroidism: a positron emission tomography study before and after thyroid hormone replacement therapy.

@article{Bauer2009BrainGM,
  title={Brain glucose metabolism in hypothyroidism: a positron emission tomography study before and after thyroid hormone replacement therapy.},
  author={Michael Bauer and Daniel H. S. Silverman and F Schlagenhauf and Edythe D. London and Cheri L. Geist and Katja van Herle and Natalie L. Rasgon and Dorothy S. Martinez and Karl Hagstrom Miller and Andre J Van Herle and Steven M. Berman and Michael E. Phelps and Peter C. Whybrow},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2009},
  volume={94 8},
  pages={2922-9}
}
CONTEXT Hypothyroidism is frequently associated with subtle behavioral and psychiatric symptoms. The consequences of inadequate thyroid hormone availability to brain metabolism are poorly understood. OBJECTIVE This study assessed the relationships between neuropsychiatric symptoms and changes in relative regional cerebral glucose metabolism in hypothyroid patients undergoing thyroid hormone replacement therapy. DESIGN, SETTING, AND OUTCOME MEASURE: Relative regional cerebral glucose… CONTINUE READING