Brain glucose metabolism in Rett Syndrome.

  title={Brain glucose metabolism in Rett Syndrome.},
  author={Patricia M Villemagne and Sakkubai R Naidu and Victor Villemagne and Myron Yaster and Henry N. Wagner and James Harris and Hugo W. Moser and Michael V Johnston and Robert F. Dannals and Dean F. Wong},
  journal={Pediatric neurology},
  volume={27 2},
Rett syndrome is a progressive neurologic disorder affecting girls in early childhood with loss of achieved psychomotor abilities and mental retardation. Six sedated female patients (4 to 15 years of age) with a diagnosis of Rett syndrome were studied with [(18)F]fluorodeoxyglucose (FDG) and underwent positron emission tomography scanning of the brain. Relative tracer concentrations between different areas of the brain were assessed, and results were compared with 18 age-matched control… CONTINUE READING