Brain function during multi-trial learning in mild cognitive impairment: a PET activation study.

@article{Moulin2007BrainFD,
  title={Brain function during multi-trial learning in mild cognitive impairment: a PET activation study.},
  author={Chris J. A. Moulin and Matti Laine and Juha O. Rinne and Valtteri Kaasinen and Hannu T. Sipil{\"a} and J. Hiltunen and Aki Kangasm{\"a}ki},
  journal={Brain research},
  year={2007},
  volume={1136 1},
  pages={132-41}
}
We explored functional brain changes with positron emission tomography (PET) in mild cognitive impairment (MCI) patients and elderly normal controls by employing an episodic memory task that included two successive encoding trials of semantically related word-pairs and final retrieval. Both groups demonstrated significant learning across the two trials. The control group showed predominantly left frontal activity during encoding, and right frontal plus left temporal activity during retrieval… CONTINUE READING