Brain expression of apolipoproteins E, J, and A-I in Alzheimer's disease.

Abstract

Inheritance of the epsilon 4 allele of apolipoprotein (apo) E is associated with increased risk of Alzheimer's disease (AD) and with increased beta-amyloid peptide (A beta) deposition in the cortex. Apo E is a member of a family of exchangeable apos, characterized by the presence of amphipathic alpha-helical segments that allow these molecules to act as… (More)

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Cite this paper

@article{Harr1996BrainEO, title={Brain expression of apolipoproteins E, J, and A-I in Alzheimer's disease.}, author={S D Harr and Luciana Uint and Richard D. Hollister and Bradley T. Hyman and Armando J. Mendez}, journal={Journal of neurochemistry}, year={1996}, volume={66 6}, pages={2429-35} }