Brain dysfunction behind functional symptoms: neuroimaging and somatoform, conversive, and dissociative disorders

  title={Brain dysfunction behind functional symptoms: neuroimaging and somatoform, conversive, and dissociative disorders},
  author={Javier Garc{\'i}a-Campayo and Nicol{\'a}s Miguel Fayed and Antoni Serrano-Blanco and Miquel Roca},
  journal={Current Opinion in Psychiatry},
Purpose of review Neuroimaging research in psychiatry has been increasing exponentially in recent years, yet many psychiatrists are relatively unfamiliar with this field. This article summarizes the findings of the most relevant research articles on the neuroimaging of somatoform, conversive, and dissociative disorders published from January 2007 through June 2008. Recent findings Neuroimaging findings summarized here include alterations of stress regulation and coping in somatoform pain… 
[Neuropsychological assessment in conversion disorder].
The present findings highlight the differences between the groups in learning and memory, executive and visuospatial functions, and attention, which seemed to be specific to conversion disorder.
The Involvement of Secondary Neuronal Damage in the Development of Neuropsychiatric Disorders Following Brain Insults
A meta-analysis supports existence of the same neuropsychiatric signs or symptoms in all brain insults and suggests that neuronal damage might be occurring in the same or similar regions or structures of the brain.
Brain Imaging in Fibromyalgia
Functional data of neural activation abnormalities parallel structural findings of gray matter atrophy, alterations of intrinsic connectivity networks, and variations in metabolites levels along multiple pathways enable the understanding of fibromyalgia pathophysiology, and favor the future establishment of more tailored treatments.
Emerging themes in the revision of the classification of somatoform disorders
The review suggests that, as currently defined, somatoform disorders do not fulfil a recently articulated set of criteria for mental and behavioural disorders and evidence is sparse to support their classification as different and distinct diagnoses.
Altered Cortical Swallowing Processing in Patients with Functional Dysphagia: A Preliminary Study
Functional dysphagia - a condition with assumed normal brain function - seems to be associated with distinctive changes of the swallow-related cortical activation pattern, which may reflect exaggerated activation of a widely distributed vigilance, self-monitoring and salience rating network that interferes with down-stream deglutition sensorimotor control.
Dysfunctional pain modulation in somatoform pain disorder patients
Results suggest decreased cortical baseline arousal in somatoform pain disorder patients, which may point to an altered baseline activity, maybe characteristic for chronic somatoforms pain disorder.
Neuropsychological Assessment in Conversion Disorder 2
The hypothesis of the study was that the patients with conversion disorder would have poorer neurocognitive performance than the controls, and the present study aimed to determine if there are differences in measures of cognitive functioning between patients with Conversion disorder and healthy controls.
Hypochondriasis and Somatization Disorder: New Perspectives
The blurred boundaries between illnesses presenting with somatic symptoms confronts both psychiatrists and primary care physicians with one of the most challenging issues in patient care, with some patients facing a chronic search for relief.
Simulated illness: the factitious disorders and malingering.
Fibromyalgia and Associated Disorders: From Pain to Chronic Suffering, From Subjective Hypersensitivity to Hypersensitivity Syndrome
It is possible to define fibromyalgia as a cognitive disorder of cortical integration of chronic pain, with amplification of painful and sensory nociception, decrease in the threshold for the perception of pain, and persistence of a stimulus that maintains the process in chronicity.


Hippocampus dysfunction may explain symptoms of fibromyalgia syndrome
The aim of the current review is to focus on the physiological roles of the hippocampus and its relation to symptoms production in FM syndrome.
Effect of abuse history on pain reports and brain responses to aversive visceral stimulation: an FMRI study.
Pain ratings during rectal distention are associated with activation of dorsal cingulate regions implicated in homeostatic afferent processing, and prior abuse enhances this activation.
Cognitive-Affective Neuroscience of Somatization Disorder and Functional Somatic Syndromes: Reconceptualizing The Triad of Depression-Anxiety-Somatic Symptoms
A review of the cognitive-affective neuroscience of Somatization disorder and related conditions suggests that overlapping psychobiological mechanisms mediate depression, anxiety, and somatization symptoms.
Accelerated Brain Gray Matter Loss in Fibromyalgia Patients: Premature Aging of the Brain?
Fibromyalgia is an intractable widespread pain disorder that is most frequently diagnosed in women. It has traditionally been classified as either a musculoskeletal disease or a psychological
Pain catastrophizing and neural responses to pain among persons with fibromyalgia.
The findings suggest that pain catastrophizing, independent of the influence of depression, is significantly associated with increased activity in brain areas related to anticipation of pain, attention to pain, and emotional aspects of pain.