Brain dopamine neurone 'damage': methamphetamine users vs. Parkinson's disease - a critical assessment of the evidence.

@article{Kish2017BrainDN,
  title={Brain dopamine neurone 'damage': methamphetamine users vs. Parkinson's disease - a critical assessment of the evidence.},
  author={Stephen J. Kish and Isabelle Boileau and Russell Clarence Callaghan and Junchao Tong},
  journal={The European journal of neuroscience},
  year={2017},
  volume={45 1},
  pages={
          58-66
        }
}
The objective of this review is to evaluate the evidence that recreational methamphetamine exposure might damage dopamine neurones in human brain, as predicted by experimental animal findings. Brain dopamine marker data in methamphetamine users can now be compared with those in Parkinson's disease, for which the Oleh Hornykiewicz discovery in Vienna of a brain dopamine deficiency is established. Whereas all examined striatal (caudate and putamen) dopamine neuronal markers are decreased in… CONTINUE READING
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