Brain development during childhood and adolescence: a longitudinal MRI study

  title={Brain development during childhood and adolescence: a longitudinal MRI study},
  author={J. Giedd and J. Blumenthal and N. Jeffries and F. Castellanos and H. Liu and A. Zijdenbos and T. Paus and Alan C. Evans and J. Rapoport},
  journal={Nature Neuroscience},
  • J. Giedd, J. Blumenthal, +6 authors J. Rapoport
  • Published 1999
  • Medicine, Biology
  • Nature Neuroscience
  • Pediatric neuroimaging studies, up to now exclusively cross sectional, identify linear decreases in cortical gray matter and increases in white matter across ages 4 to 20. In this large-scale longitudinal pediatric neuroimaging study, we confirmed linear increases in white matter, but demonstrated nonlinear changes in cortical gray matter, with a preadolescent increase followed by a postadolescent decrease. These changes in cortical gray matter were regionally specific, with developmental… CONTINUE READING

    Figures, Tables, and Topics from this paper.

    Paper Mentions

    The purpose of this project is to test the effectiveness of a novel school-based intervention targeting executive function skills, including flexibility and planning, in college-track… Expand
    ConditionsAutism Spectrum Disorder
    InterventionBehavioral, Other
    Brain development in children and adolescents: Insights from anatomical magnetic resonance imaging
    • 1,322
    • PDF
    Microstructural maturation of the human brain from childhood to adulthood
    • 1,058
    • Highly Influenced
    • PDF
    Mapping brain maturation
    • 734
    • PDF
    White matter development during childhood and adolescence: a cross-sectional diffusion tensor imaging study.
    • 721
    • PDF
    Structural Magnetic Resonance Imaging of the Adolescent Brain
    • 1,309
    Longitudinal Development of Human Brain Wiring Continues from Childhood into Adulthood
    • 743
    • Highly Influenced
    • PDF
    Sexual dimorphism of brain developmental trajectories during childhood and adolescence
    • 957
    • PDF


    Publications referenced by this paper.