Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells.

@article{Johnson1986BrainderivedNF,
  title={Brain-derived neurotrophic factor supports the survival of cultured rat retinal ganglion cells.},
  author={Jane E Johnson and Y. - A. Barde and Martin E. Schwab and Hans Thoenen},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1986},
  volume={6 10},
  pages={3031-8}
}
Brain-derived neurotrophic factor (BDNF) is a small, basic protein purified from the mammalian brain that has been shown previously to support the survival of cultured spinal sensory neurons (Barde et al., 1982). In current studies, BDNF was tested for its ability to support the survival of cultured CNS cells isolated from the perinatal rat retina. Both immunofluorescent labeling of Thy-1 and prior retrograde labeling with HRP were used as retinal ganglion cell markers in vitro. With embryonic… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 130 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 41 references

Neurotrophic factors

  • J. E. Turner
  • Science
  • 1985
1 Excerpt

Similar Papers

Loading similar papers…