Brain-derived neurotrophic factor reduces necrotic zone and supports neuronal survival after spinal cord hemisection in adult rats.

Abstract

Spinal cord injury (SCI) often results in necrotic changes leading to cavity formation and glial scar tissue in the lesion zone. We have examined the effects of continuous topical administration of brain-derived neurotrophic factor (BDNF) on cavity formation and neuronal death after SCI. Following retrograde prelabeling of the tibial motoneurons in the L4… (More)

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Cite this paper

@article{Novikova1996BrainderivedNF, title={Brain-derived neurotrophic factor reduces necrotic zone and supports neuronal survival after spinal cord hemisection in adult rats.}, author={Liudmila N. Novikova and Lev N. Novikov and J O Kellerth}, journal={Neuroscience letters}, year={1996}, volume={220 3}, pages={203-6} }