Brain-derived neurotrophic factor expression is increased in the rat amygdala, piriform cortex and hypothalamus following repeated amphetamine administration.

@article{Meredith2002BrainderivedNF,
  title={Brain-derived neurotrophic factor expression is increased in the rat amygdala, piriform cortex and hypothalamus following repeated amphetamine administration.},
  author={Gloria E. Meredith and Shannon Callen and Deborah A. Scheuer},
  journal={Brain research},
  year={2002},
  volume={949 1-2},
  pages={218-27}
}
The amygdala plays an important role in the regulation of motivational states, especially those associated with addiction. The amygdala also expresses high levels of brain-derived neurotrophic factor (BDNF), an activity-dependent neurotrophin that can influence the reinforcing and locomotor activating properties of psychostimulants. In the present study, we examined the effects of acute and repeated amphetamine administration on the expression and production of this factor in the forebrain of… CONTINUE READING

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