Brain-derived neurotrophic factor (BDNF) and neurocognitive deficits in people with schizophrenia: a meta-analysis.

@article{Ahmed2015BrainderivedNF,
  title={Brain-derived neurotrophic factor (BDNF) and neurocognitive deficits in people with schizophrenia: a meta-analysis.},
  author={Anthony Olufemi Ahmed and Andrew M Mantini and Daniel J Fridberg and Peter Buckley},
  journal={Psychiatry research},
  year={2015},
  volume={226 1},
  pages={
          1-13
        }
}
Studies suggest that the BDNF Val66Met (rs6265) polymorphism is associated with the incidence of schizophrenia and neurocognitive functioning. These associations appear to be however somewhat mixed. We conducted two separate meta-analyses to investigate (1) the association between the Val66Met polymorphism and neurocognition in people with schizophrenia and (2) the association between peripheral expression of BDNF and neurocognitive phenotypes. For the first aim, we identified 12 studies and 67… CONTINUE READING

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