Brain changes in early-onset bipolar and unipolar depressive disorders: a systematic review in children and adolescents

@article{Serafini2014BrainCI,
  title={Brain changes in early-onset bipolar and unipolar depressive disorders: a systematic review in children and adolescents},
  author={G. Serafini and M. Pompili and S. Borgwardt and J. Houenou and P. Geoffroy and R. Jardri and P. Girardi and M. Amore},
  journal={European Child \& Adolescent Psychiatry},
  year={2014},
  volume={23},
  pages={1023-1041}
}
Pediatric bipolar disorder (BD) and unipolar disorder (UD) share common symptomatic and functional impairments. Various brain imaging techniques have been used to investigate the integrity of brain white matter (WM) and gray matter (GM) in these disorders. Despite promising preliminary findings, it is still unclear whether these alterations may be considered as common trait markers or may be used to distinguish BD from UD. A systematic literature search of studies between 1980 and September… Expand
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Topologically convergent and divergent functional connectivity patterns in unmedicated unipolar depression and bipolar disorder
  • Y Wang, J. Wang, +9 authors R. Huang
  • Psychology, Medicine
  • Translational Psychiatry
  • 2017
Bipolar disorder (BD), particularly BD II, is frequently misdiagnosed as unipolar depression (UD), leading to inappropriate treatment and poor clinical outcomes. Although depressive symptoms may beExpand
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