Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer’s disease

@inproceedings{Jack2010BrainBM,
  title={Brain beta-amyloid measures and magnetic resonance imaging atrophy both predict time-to-progression from mild cognitive impairment to Alzheimer’s disease},
  author={Clifford R. Jack and Heather J. Wiste and Prashanthi Vemuri and Stephen D. Weigand and Matthew L. Senjem and Guang Zeng and Matt A. Bernstein and Jeffrey L. Gunter and V. Shane Pankratz and Paul S. Aisen and Michael W Weiner and Ronald C. Petersen and Leslie M. Shaw and John Q. Trojanowski and David S. Knopman},
  booktitle={Brain : a journal of neurology},
  year={2010}
}
Biomarkers of brain Aβ amyloid deposition can be measured either by cerebrospinal fluid Aβ42 or Pittsburgh compound B positron emission tomography imaging. Our objective was to evaluate the ability of Aβ load and neurodegenerative atrophy on magnetic resonance imaging to predict shorter time-to-progression from mild cognitive impairment to Alzheimer's dementia and to characterize the effect of these biomarkers on the risk of progression as they become increasingly abnormal. A total of 218… CONTINUE READING
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Transforming CSF Ab42 measures into calculated PIB (PIBcalc) units of brain

  • SD Weigand, P Vemuri, HJ Wiste, ML Senjem, S Pankratz, S Aisen
  • Ab amyloid. Rochester; MN, San Francisco; CA…
  • 2010
Highly Influential
3 Excerpts

Survival: survival analysis, including penalized likelihood

  • T. Therneau
  • Vienna, Austria: R Foundation for Statistical…
  • 2008
Highly Influential
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