Brain atrophy in relapsing-remitting multiple sclerosis and secondary progressive multiple sclerosis: longitudinal quantitative analysis.

@article{Ge2000BrainAI,
  title={Brain atrophy in relapsing-remitting multiple sclerosis and secondary progressive multiple sclerosis: longitudinal quantitative analysis.},
  author={Yulin Ge and Robert I. Grossman and Jayaram K. Udupa and L Wei and Lois J Mannon and Marcia Polansky and Dennis L Kolson},
  journal={Radiology},
  year={2000},
  volume={214 3},
  pages={665-70}
}
PURPOSE To determine annual rates of volumetric changes in the whole-brain parenchyma of patients with relapsing-remitting and secondary progressive multiple sclerosis (MS) and test the hypothesis that these changes correlate with clinical disability. MATERIALS AND METHODS A computer-assisted segmentation technique with thin-section magnetic resonance (MR) imaging was used in 36 patients with MS (27 relapsing-remitting, nine secondary progressive) and in 20 control subjects to quantify brain… CONTINUE READING