Brain apparent diffusion coefficient evaluation in pediatric patients with neurofibromatosis type 1.

@article{Tognini2005BrainAD,
  title={Brain apparent diffusion coefficient evaluation in pediatric patients with neurofibromatosis type 1.},
  author={Giuseppe Tognini and Francesco Ferrozzi and Giacomo Garlaschi and Paolo Piazza and Arianna Patti and Raffaele Virdis and Chiara Bertolino and Giancarlo Bertolino and Daniele Manfredini and Maurizio Zompatori and Girolamo Crisi},
  journal={Journal of computer assisted tomography},
  year={2005},
  volume={29 3},
  pages={298-304}
}
OBJECTIVE The most frequent intracranial appearance in children with neurofibromatosis type 1 (NF1) is represented by the presence of hyperintense lesions on T2-weighted images, the so-called "unidentified bright objects" (UBOs). Di Paolo demonstrated that these lesions represent foci of myelin vacuolization with increased water content. The aim of this study was to investigate the isotropic apparent diffusion coefficient (ADC) values within the UBOs and normal-appearing brain and at the… CONTINUE READING

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