Brain and platelet serotonin transporter in humans-correlation between [123I]-ADAM SPECT and serotonergic measurements in platelets.

@article{Uebelhack2006BrainAP,
  title={Brain and platelet serotonin transporter in humans-correlation between [123I]-ADAM SPECT and serotonergic measurements in platelets.},
  author={Ralf Uebelhack and Leonora Franke and Nathalie Herold and Michael A Plotkin and Holger Amthauer and Roland Felix},
  journal={Neuroscience letters},
  year={2006},
  volume={406 3},
  pages={153-8}
}
Blood platelets are thought to be a useful peripheral model for investigating the central serotoninergic mechanisms associated with the serotonin transporter (SERT). On the other hand, an in vivo investigation of SERT in the human brain has been made possible by the development of several promising SPECT radioligands, such as [123I]-ADAM. The aim of the present study was to investigate the possible correlation between the SERT measurements in the brain and those in platelets. Forty-four… CONTINUE READING
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