Brain aging modulates the neuroprotective effects of estrogen on selective aspects of cognition in women: a critical review.

@article{Sherwin2008BrainAM,
  title={Brain aging modulates the neuroprotective effects of estrogen on selective aspects of cognition in women: a critical review.},
  author={Barbara B. Sherwin and Jessica F Henry},
  journal={Frontiers in neuroendocrinology},
  year={2008},
  volume={29 1},
  pages={88-113}
}
Although there is now a substantial literature on the putative neuroprotective effects of estrogen on cognitive functioning in postmenopausal women, it is replete with inconsistencies. The critical period hypothesis, posited several years ago, attempts to account for the discrepancies in this literature by positing that estrogen treatment (ET) will protect aspects of cognition in older women only when treatment is initiated soon after the menopause. Indeed, evidence from basic neuroscience and… CONTINUE READING
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