• DOI:10.1111/j.1528-1157.1998.tb01188.x
• Corpus ID: 22256852

Brain Thyrotropin‐Releasing Hormone Content Varies Through Amygdaloid Kindling Development According to Afterdischarge Frequency and Propagation

@article{Gortari1998BrainTH,
  title={Brain Thyrotropin‐Releasing Hormone Content Varies Through Amygdaloid Kindling Development According to Afterdischarge Frequency and Propagation},
  author={Patricia de Gortari and Patricia Joseph-Bravo and Jos{\'e} Monroy-Ruiz and A. Mart{\'i}nez and Miguel Cisneros and Augusto Fern{\'a}ndez Guardiola},
  journal={Epilepsia},
  year={1998},
  volume={39}
}

• P. Gortari, P. Joseph-Bravo, +3 authors A. F. Guardiola
• Published 1 August 1998
• Biology
• Epilepsia

Summary: Purpose: Thyrotropin‐releasing hormone (TRH), present in extra hypothalamic brain areas, has been proposed to have neuromodulatory functions and to be susceptible to change by electrical stimulation paradigms. We measured TRH concentrations of several brain areas during kindling development before its establishment and determined whether the changes detected in TRH levels were related to the behavioral stages of kindling, the number of stimulations required to reach these stages and, with the electrophysiological parameters characteristic of this paradigm (amygdaloid afterdischarge (AD) frequency, duration, and propagation).