Brain Thyrotropin‐Releasing Hormone Content Varies Through Amygdaloid Kindling Development According to Afterdischarge Frequency and Propagation

@article{Gortari1998BrainTH,
  title={Brain Thyrotropin‐Releasing Hormone Content Varies Through Amygdaloid Kindling Development According to Afterdischarge Frequency and Propagation},
  author={Patricia de Gortari and Patricia Joseph-Bravo and Jos{\'e} Monroy-Ruiz and A. Mart{\'i}nez and Miguel Cisneros and Augusto Fern{\'a}ndez Guardiola},
  journal={Epilepsia},
  year={1998},
  volume={39}
}
Summary: Purpose: Thyrotropin‐releasing hormone (TRH), present in extra hypothalamic brain areas, has been proposed to have neuromodulatory functions and to be susceptible to change by electrical stimulation paradigms. We measured TRH concentrations of several brain areas during kindling development before its establishment and determined whether the changes detected in TRH levels were related to the behavioral stages of kindling, the number of stimulations required to reach these stages and… 

Stage-specific Modulation of Neprilysin and Aminopeptidase N in the Limbic System During Kindling Progression

Results demonstrate that expression of ectopeptidases can be regulated when peptide neurons are activated and, that regulation is enzyme-, region-, and stage-specific.

Effect of Fasting on the Content of Thyrotropin-releasing Hormone and its mRNA in the Central Nervous System and Pyroglutamyl Peptidase II Activity in the Anterior Pituitary of Post-Weaned and Adult Rats

A differential regulation of TRH metabolism by fasting dependent on the age of the animals is shown, which is in line with previous studies of fasting and malnutrition.

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