Brain Susceptibility Changes in a Patient with Natalizumab-Related Progressive Multifocal Leukoencephalopathy: A Longitudinal Quantitative Susceptibility Mapping and Relaxometry Study

@inproceedings{Pontillo2017BrainSC,
  title={Brain Susceptibility Changes in a Patient with Natalizumab-Related Progressive Multifocal Leukoencephalopathy: A Longitudinal Quantitative Susceptibility Mapping and Relaxometry Study},
  author={Giuseppe Pontillo and Sirio Cocozza and Roberta Lanzillo and Pasquale Borrelli and Anna De Rosa and Vincenzo Brescia Morra and Enrico Tedeschi and Giuseppe Palma},
  booktitle={Front. Neurol.},
  year={2017}
}
BACKGROUND Brain MRI plays an essential role in both diagnosis and follow-up of the JC virus infection of the brain. Recently, MR studies with susceptibility-weighted imaging (SWI) sequences have shown hypointensities in U-fibers adjacent to white matter (WM) lesions of progressive multifocal leukoencephalopathy (PML). This finding has been confirmed with the use of quantitative susceptibility mapping (QSM), allowing to hypothesize a paramagnetic effect in these regions. Here, we report the… CONTINUE READING
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Publications referenced by this paper.
SHOWING 1-10 OF 27 REFERENCES

Natalizumab - induced POU 2 AF 1 / Spi - B upregulation : a possible route for PML development

M Meira, C Sievers, +3 authors BF Décard
  • Neurol Neuroimmunol Neuroinflamm
  • 2016

a possible route for PML development

M Meira, C Sievers, +4 authors upregulation et al. Natalizumab-induced POU2AF1Spi-B
  • Neurol Neuroimmunol Neuroinflamm
  • 2016