Brain Insulin Resistance at the Crossroads of Metabolic and Cognitive Disorders in Humans.

@article{Kullmann2016BrainIR,
  title={Brain Insulin Resistance at the Crossroads of Metabolic and Cognitive Disorders in Humans.},
  author={Stephanie Kullmann and Martin Heni and Manfred Hallschmid and Andreas Fritsche and Hubert Preissl and Hans-Ulrich H{\"a}ring},
  journal={Physiological reviews},
  year={2016},
  volume={96 4},
  pages={
          1169-209
        }
}
Ever since the brain was identified as an insulin-sensitive organ, evidence has rapidly accumulated that insulin action in the brain produces multiple behavioral and metabolic effects, influencing eating behavior, peripheral metabolism, and cognition. Disturbances in brain insulin action can be observed in obesity and type 2 diabetes (T2D), as well as in aging and dementia. Decreases in insulin sensitivity of central nervous pathways, i.e., brain insulin resistance, may therefore constitute a… CONTINUE READING
25 Citations
403 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 25 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 403 references

Intranasal KULLMANN ET AL

  • S Craft, LD Baker, +11 authors B. Gerton
  • Physiol Rev • VOL
  • 2012
Highly Influential
6 Excerpts

Similar Papers

Loading similar papers…